Van de Ven Brace Halts The Toffees' Unbeaten Streak at New Home Ground
The Dutch defender became the initial backline player to score twice in a English top-flight match for Spurs since Jan Vertonghen in March 2013.
Match summary
Micky Van de Ven heads into the net two times in opening period
Everton's Jake O'Brien has goal disallowed after VAR review
Pape Matar Sarr scores third in dying moments
The defeat is Everton's first at their new ground
The Tottenham defender scored on two occasions as Spurs prolonged their winning streak in away games in the top division and handed the Toffees their first defeat at Hill Dickinson Stadium.
The Toffees were unbeaten in their five previous fixtures at their new ground at the dockside location, having left Goodison Park behind after more than a century at the conclusion of last season.
But Spurs captain Van de Ven struck twice from set-pieces in the first half to place their strong form at risk, and they were failed to mount a comeback before Pape Matar Sarr - set up by former Toffees attacker the Brazilian - headed home a third to seal the victory.
The Everton defender thought he had equalized the scores five minutes after the defender's first goal, directing a bullet header past Guglielmo Vicario from an Everton corner.
Beto, meanwhile, missed a number of opportunities, while the Italian goalkeeper made a succession of fine stops to guarantee Tottenham went five away games without defeat in the Premier League.
But the VAR intervened, advising Craig Pawson to review the goal on the screen and the referee decided that Jack Grealish and the attacker were in offside positions and had impeded with the Tottenham goalkeeper.
The win elevates Thomas Frank's team into third place in the division, a handful of points off local foes and leaders the Gunners.
The Merseyside club remain 14th and are six points clear of the relegation zone.
Spurs breakdown: The defender excels in duties at both ends of pitch
Following a drab weekday performance in the European competition against Monaco, where they managed a only attempts on goal, the manager opted for Randal Kolo Muani in attack instead of ex-Everton forward Richarlison.
The summer signing was unable to influence the game before being replaced for the substitute after an hour on the pitch, but it turns out he wasn't needed in the end.
Defender Van de Ven transformed into an offensive threat to be reckoned with.
Tottenham's opening strike came from a well-worked set-piece play, with the midfielder directing the ball back across the face of goal for an free the defender to head home.
And the captain - filling in as captain in Cristian Romero's absence - notched his second in first-half stoppage time as he outjumped Jordan Pickford to nod in.
The Dutchman was equally outstanding in defensive duties, partnering well with his defensive colleague as the pair dealt excellently with the numerous deliveries sent their way by Everton.
Everton analysis: Toffees lacking striker's instinct
Everton's new home had been a fortress, but it seems the novelty may have worn off somewhat and supporters flocked to the gates after the midfielder's final goal for Spurs.
The break in Everton's unbeaten home run won't be a massive worry for David Moyes, but their attacking woes will be.
The forward and Thierno Barry - the Toffees' two established strikers - had scored only a single goal between them before the weekend's match.
And they were unable to contribute to that poor record on a wet and gloomy night on Merseyside.
Beto's performance was epitomized when he opted to overhead kick a clear chance from close range, despite having space and time to reposition for a simpler attempt that would have tested the keeper.
Barry, as well, was unable to influence the game after coming on for the starter in the second half.
It wasn't for a shortage of chance. The majority of Everton's attacks came through the winger and Ndiaye, who tirelessly whipped dangerous crosses into the Tottenham box.
Upcoming fixtures for these two sides?
Everton: Moyes' men travel to Sunderland in the top flight on early November at 20:00 GMT.
Spurs: Spurs travel to St James' Park on late October for their next round Carabao Cup match against Newcastle.